1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor used in the therapy of various myeloma. Its synthesis or analyze is very important for guaranteeing the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound inside the synthesis of imatinib, a drug that targets particular types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is vital for optimizing the production course of action and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is used to deal with breast most cancers, and these 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist used in the remedy of breast most cancers. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy 4-[2-(2-Amino-4 drug Utilized in the treatment of colorectal cancer and modest mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have a variety of apps, together with antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, which might be Employed in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication utilized to manage kind 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).